Different types of statins might act differently in reducing plasma asymmetric dimethylarginine levels. Authors' reply

Different types of statins might act differently in reducing plasma asymmetric dimethylarginine levels.

POLSKIE ARCHIWUM MEDYCYNY WEWNĘTRZNEJ 2013; 123 (10) To the Editor We read the article by Szpak et al.1 with interest. The authors investigated whether active or passive tobacco smoking may affect en‐ dothelial dysfunction markers such as asymme‐ tric dimethylarginine (ADMA), thrombomodulin (TM), plasminogen activator inhibitor‐1 (PAI‐1), and cotinine levels in patients with advanced co‐ ronary...

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A systematic review and meta-analysis of the effect of statins on plasma asymmetric dimethylarginine concentrations

The impact of statin therapy on plasma asymmetric dimethylarginine (ADMA) levels has not been conclusively studied. Therefore the aim of the meta-analysis was to assess the effect of statins on circulating ADMA levels. We searched selected databases (up to August 2014) to identify randomized controlled trials (RCTs) that investigate the effect of statins on plasma ADMA concentrations. A weighte...

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